<p><strong>Po prvÃ½krÃ¡t v histÃ³rii sa podarilo oÅ¾iviÅ¥ vyhynutÃ© zviera â€“ vlka hroznÃ©ho (zvanÃ©ho aj pravlk obrovskÃ½). VÄaka genetickÃ©mu inÅ¾inierstvu a pouÅ¾itiu starodÃ¡vnej DNA americkÃ¡ spoloÄnosÅ¥ Colossal Biosciences priviedla na svet tri mlÃ¡ÄatÃ¡ tohto ikonickÃ©ho predÃ¡tora</strong></p>
<p></p>
<p>Colossal Biosciences, biotechnologickÃ¡ spoloÄnosÅ¥ so sÃ­dlom v Dallase, oznÃ¡mila prevratnÃ½ Ãºspech: <a href="https://interestingengineering.com/innovation/dire-wolves-return-after-13000-years" target="_blank" rel="noopener">znovuzrodenie vlka hroznÃ©ho</a> (Aenocyon dirus), ktorÃ½ vymrel pred pribliÅ¾ne 12 500 rokmi. VÄaka kombinÃ¡cii pokroÄilÃ½ch genetickÃ½ch technÃ­k sa podarilo priniesÅ¥ na svet tri vlÄie mlÃ¡ÄatÃ¡ s gÃ©nmi vlka hroznÃ©ho. Tento druh bol v minulosti jednÃ½m z najvÃ¤ÄÅ¡Ã­ch predÃ¡torov Severnej Ameriky a inÅ¡piroval mnoÅ¾stvo popkultÃºrnych diel vrÃ¡tane seriÃ¡lu Hra o trÃ³ny.</p>
<h2>Ako podarilo oÅ¾iviÅ¥ vyhynutÃ©ho vlka hroznÃ©ho?</h2>
<p>VedeckÃ½ tÃ­m pod vedenÃ­m Colossal Biosciences najprv analyzoval starodÃ¡vnu DNA extrahovanÃº z dvoch fosÃ­liÃ­ â€“ 13 000 rokov starÃ©ho zubu z Ohia a 72 000 rokov starÃ©ho vnÃºtornÃ©ho ucha z Idaha. Pomocou metÃ³dy iteratÃ­vnej genÃ³movej montÃ¡Å¾e sa podarilo vytvoriÅ¥ najkompletnejÅ¡Ã­ genÃ³m vlka hroznÃ©ho v histÃ³rii. VÃ½sledky ukÃ¡zali, Å¾e vlk hroznÃ½ mÃ¡ 99,5 % gÃ©novej zhody s dnes Å¾ijÃºcim sivÃ½m vlkom.</p>
<p>Nasledovalo genetickÃ© inÅ¾inierstvo, pri ktorom vedci vykonali 20 presnÃ½ch Ãºprav na 14 <a href="https://wp.techguru.sk/co-je-lokus/" target="_blank" rel="noopener">lokusoch</a>. Tieto modifikÃ¡cie, vrÃ¡tane 15 zaniknutÃ½ch genetickÃ½ch variantov, umoÅ¾nili vytvoriÅ¥ bunkovÃ© lÃ­nie obsahujÃºce poÅ¾adovanÃ© gÃ©ny. NÃ¡sledne sa najÅ¾ivotaschopnejÅ¡ie bunky klonovali pomocou somatickÃ©ho prenosu jadra a implantovali do vajÃ­Äok darcovskÃ½ch zvierat.</p>


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			<div id="su-post-28981" class="su-post ">

									<a class="su-post-thumbnail" href="https://wp.techguru.sk/28981/univerzita-prijala-prveho-ai-studenta/"><img loading="lazy" decoding="async" width="1200" height="685" src="https://wp.techguru.sk/wp-content/uploads/2025/04/Vieden-prvy-AI-student-Flynn.jpg" class="attachment-post-thumbnail size-post-thumbnail wp-post-image" alt="ViedenskÃ¡ univerzita prijala prvÃ©ho AI Å¡tudenta. Bude Å¡tudovaÅ¥ spolu s Ä¾uÄmi" srcset="https://wp.techguru.sk/wp-content/uploads/2025/04/Vieden-prvy-AI-student-Flynn.jpg 1200w, https://wp.techguru.sk/wp-content/uploads/2025/04/Vieden-prvy-AI-student-Flynn-300x171.jpg 300w, https://wp.techguru.sk/wp-content/uploads/2025/04/Vieden-prvy-AI-student-Flynn-1024x585.jpg 1024w, https://wp.techguru.sk/wp-content/uploads/2025/04/Vieden-prvy-AI-student-Flynn-768x438.jpg 768w" sizes="auto, (max-width: 1200px) 100vw, 1200px" /></a>
				
				<h2 class="su-post-title"><a href="https://wp.techguru.sk/28981/univerzita-prijala-prveho-ai-studenta/">ViedenskÃÂ¡ univerzita prijala prvÃÂ©ho AI ÃÂ¡tudenta. Bude ÃÂ¡tudovaÃÂ¥ spolu s ÃÂ¾uÃÂmi</a></h2>

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					Posted: 7. apríla 2025				</div>

				<div class="su-post-excerpt">
					<p>Univerzita aplikovanÃ½ch umenÃ­ vo Viedni ako prvÃ¡ na svete prijala umelÃº inteligenciu ako oficiÃ¡lneho AI Å¡tudenta digitÃ¡lneho umenia. UmelÃ¡ inteligencia s nÃ¡zvom Flynn sa bude zÃºÄastÅˆovaÅ¥ prednÃ¡Å¡ok a dostÃ¡vaÅ¥ znÃ¡mky rovnako ako Ä¾udskÃ­ Å¡tudenti</p>
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<p>Po ÃºspeÅ¡nej interÅ¡pecifickej nÃ¡hradnej gravidite sa narodili tri mlÃ¡ÄatÃ¡: dvaja samci Romulus a Remus a samiÄka Khaleesi. Tieto mlÃ¡ÄatÃ¡ sÃº prvÃ½mi ÃºspeÅ¡ne oÅ¾ivenÃ½mi jedincami vyhynutÃ©ho druhu.</p>
<figure id="attachment_29005" class="thumbnail wp-caption aligncenter" style="width: 707px"><a href="https://wp.techguru.sk/wp-content/uploads/2025/04/znovuzrodenie-vlka-hrozneho-vyhynuteho-02-Romulus.jpg" data-rel="lightbox-gallery-9Vdi7q1P" data-rl_title="" data-rl_caption="" title=""><img loading="lazy" decoding="async" class="size-large wp-image-29005" src="https://wp.techguru.sk/wp-content/uploads/2025/04/znovuzrodenie-vlka-hrozneho-vyhynuteho-02-Romulus-1024x902.jpg" alt="" width="697" height="614" srcset="https://wp.techguru.sk/wp-content/uploads/2025/04/znovuzrodenie-vlka-hrozneho-vyhynuteho-02-Romulus-1024x902.jpg 1024w, https://wp.techguru.sk/wp-content/uploads/2025/04/znovuzrodenie-vlka-hrozneho-vyhynuteho-02-Romulus-300x264.jpg 300w, https://wp.techguru.sk/wp-content/uploads/2025/04/znovuzrodenie-vlka-hrozneho-vyhynuteho-02-Romulus-768x676.jpg 768w, https://wp.techguru.sk/wp-content/uploads/2025/04/znovuzrodenie-vlka-hrozneho-vyhynuteho-02-Romulus.jpg 1200w" sizes="auto, (max-width: 697px) 100vw, 697px" /></a><figcaption class="caption wp-caption-text">Romulus &#8211; mesaÄnÃ© Å¡teniatko vlka hroznÃ©ho.</figcaption></figure>
<h2>GenetickÃ© a etickÃ© otÃ¡zky</h2>
<p>Hoci ide o vÃ½znamnÃ½ vedeckÃ½ Ãºspech, objav vyvolÃ¡va otÃ¡zky. PodÄ¾a niektorÃ½ch odbornÃ­kov nejde o skutoÄnÃ©ho vlka hroznÃ©ho, ale o geneticky modifikovanÃ©ho sivÃ©ho vlka s fenotypom vlka hroznÃ©ho. Profesor evoluÄnej genetiky Love DalÃ©n tvrdÃ­, Å¾e zmena dostatoÄnÃ©ho poÄtu gÃ©nov na vytvorenie autentickÃ©ho vlka hroznÃ©ho je skÃ´r filozofickÃ¡ otÃ¡zka.</p>
<p>Nie vÅ¡etci sÃº nadÅ¡enÃ­. Oponenti upozorÅˆujÃº na rizikÃ¡ spojenÃ© s takÃ½mito experimentmi, najmÃ¤ ak by geneticky upravenÃ© zvieratÃ¡ boli vypustenÃ© do voÄ¾nej prÃ­rody. Colossal Biosciences vÅ¡ak deklaruje, Å¾e vÅ¡etky vlky budÃº Å¾iÅ¥ v prÃ­sne monitorovanom prÃ­rodnom rezervÃ¡te o rozlohe 2 000 akrov s vysokou ÃºrovÅˆou zabezpeÄenia. (NepripomÃ­na vÃ¡m to JurskÃ½ park? &#8211; pozn.red.)</p>


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			<div id="su-post-28892" class="su-post ">

									<a class="su-post-thumbnail" href="https://wp.techguru.sk/28892/ceske-dediny-naval-turistov-kingdom-come-deliverance-ii/"><img loading="lazy" decoding="async" width="1200" height="685" src="https://wp.techguru.sk/wp-content/uploads/2025/03/kingdom-come-deliverance-2-ceske-dediny-turisti.jpg" class="attachment-post-thumbnail size-post-thumbnail wp-post-image" alt="Kingdom Come: Deliverance II" srcset="https://wp.techguru.sk/wp-content/uploads/2025/03/kingdom-come-deliverance-2-ceske-dediny-turisti.jpg 1200w, https://wp.techguru.sk/wp-content/uploads/2025/03/kingdom-come-deliverance-2-ceske-dediny-turisti-300x171.jpg 300w, https://wp.techguru.sk/wp-content/uploads/2025/03/kingdom-come-deliverance-2-ceske-dediny-turisti-1024x585.jpg 1024w, https://wp.techguru.sk/wp-content/uploads/2025/03/kingdom-come-deliverance-2-ceske-dediny-turisti-768x438.jpg 768w" sizes="auto, (max-width: 1200px) 100vw, 1200px" /></a>
				
				<h2 class="su-post-title"><a href="https://wp.techguru.sk/28892/ceske-dediny-naval-turistov-kingdom-come-deliverance-ii/">ÃÅeskÃÂ© dediny zaÃÂ¾ÃÂ­vajÃÂº nÃÂ¡val turistov pre Kingdom Come: Deliverance II. NiektorÃÂ­ starostovia nie sÃÂº nadÃÂ¡enÃÂ­</a></h2>

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					Posted: 10. marca 2025				</div>

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					<p>Obce, ktorÃ© donedÃ¡vna poznali len miestni, sa â€žcez nocâ€œ stali stredobodom pozornosti. Videohra Kingdom Come: Deliverance II, ktorÃº v tomto roku vydalo ÄeskÃ© Å¡tÃºdio Warhorse, ich premenila na magnet pre fanÃºÅ¡ikov virtuÃ¡lneho stredoveku. Hoci sa niektorÃ­ starostovia teÅ¡ia z novÃ©ho zÃ¡ujmu, inÃ­ rieÅ¡ia narastajÃºce problÃ©my s nÃ¡vÅ¡tevnÃ­kmi</p>
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<h2>Pri de-extinkcii nejde len o vlka hroznÃ©ho</h2>
<p>SpoloÄnosÅ¥ Colossal sa nezastavuje pri vlkovi hroznom. UÅ¾ dlhÅ¡ie pracuje na oÅ¾ivenÃ­ mamuta srstnatÃ©ho, ktorÃ©ho prvÃ© mlÃ¡ÄatÃ¡ plÃ¡nuje priviesÅ¥ na svet do roku 2028. Rovnako sa podieÄ¾a na ochrane kriticky ohrozenÃ©ho ÄervenÃ©ho vlka, priÄom uÅ¾ ÃºspeÅ¡ne klonovala Å¡tyri mlÃ¡ÄatÃ¡ z rÃ´znych genetickÃ½ch lÃ­niÃ­.</p>
<figure id="attachment_29003" class="thumbnail wp-caption aligncenter" style="width: 707px"><a href="https://wp.techguru.sk/wp-content/uploads/2025/04/aenocyon-dirus-vlk-hrozny-pavlk-obrovsky.jpg" data-rel="lightbox-gallery-9Vdi7q1P" data-rl_title="" data-rl_caption="" title=""><img loading="lazy" decoding="async" class="size-large wp-image-29003" src="https://wp.techguru.sk/wp-content/uploads/2025/04/aenocyon-dirus-vlk-hrozny-pavlk-obrovsky-1024x768.jpg" alt="V USA znovuzrodili vlka hroznÃ©ho z Hry o trÃ³ny" width="697" height="523" srcset="https://wp.techguru.sk/wp-content/uploads/2025/04/aenocyon-dirus-vlk-hrozny-pavlk-obrovsky-1024x768.jpg 1024w, https://wp.techguru.sk/wp-content/uploads/2025/04/aenocyon-dirus-vlk-hrozny-pavlk-obrovsky-300x225.jpg 300w, https://wp.techguru.sk/wp-content/uploads/2025/04/aenocyon-dirus-vlk-hrozny-pavlk-obrovsky-768x576.jpg 768w, https://wp.techguru.sk/wp-content/uploads/2025/04/aenocyon-dirus-vlk-hrozny-pavlk-obrovsky-640x480.jpg 640w, https://wp.techguru.sk/wp-content/uploads/2025/04/aenocyon-dirus-vlk-hrozny-pavlk-obrovsky.jpg 1280w" sizes="auto, (max-width: 697px) 100vw, 697px" /></a><figcaption class="caption wp-caption-text">Tu vidÃ­te, preÄo je vlk hroznÃ½ nazÃ½vanÃ½ aj pravlk obrovskÃ½.</figcaption></figure>
<p>PodÄ¾a vedÃºcej vedeckej pracovnÃ­Äky Beth Shapirovej mÃ¡ technolÃ³gia de-extinkcie potenciÃ¡l nielen v oÅ¾ivenÃ­ vyhynutÃ½ch druhov, ale aj v ochrane sÃºÄasne ohrozenÃ½ch zvierat. Tento vedeckÃ½ pokrok by mohol prispieÅ¥ k zachovaniu biodiverzity v Äase masovÃ©ho vymierania.</p>
<p>Colossal Biosciences plÃ¡nuje vyuÅ¾iÅ¥ svoje technolÃ³gie aj v zdravotnÃ­ctve a zÃ¡chrane ÄalÅ¡Ã­ch druhov. Vedci vÅ¡ak upozorÅˆujÃº na potrebu opatrnosti pri manipulÃ¡cii s gÃ©nmi a dÃ´kladnom zvÃ¡Å¾enÃ­ potenciÃ¡lnych nÃ¡sledkov.</p>
<div align="center"><strong>Ak Å¥a bavÃ­me, podpor nÃ¡s a kÃºp nÃ¡m pivo za 2â‚¬:</strong> <script type="text/javascript" src="https://cdnjs.buymeacoffee.com/1.0.0/button.prod.min.js" data-name="bmc-button" data-slug="techguruskcz" data-color="#66cc33" data-emoji="ðŸº" data-font="Inter" data-text="KÃºp nÃ¡m pivo" data-outline-color="#000000" data-font-color="#000000" data-coffee-color="#FFDD00" ></script></div>
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<h2 style="text-align: center;">StaÅˆ sa sÃºÄasÅ¥ou aktÃ­vnej komunity TechGuru SK/CZ na <a href="https://www.facebook.com/TechGuruSKCZ">Facebooku</a> a na <a href="https://www.instagram.com/techguruskcz/">Instagrame</a>.</h2>
<h2 style="text-align: center;">NÃ¡jdeÅ¡ nÃ¡s aj na <a href="https://www.youtube.com/channel/UC2t9gqN1hXklJmbO_aCthsA">YouTube</a></h2>
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V USA znovuzrodili vlka hroznÃ©ho z Hry o trÃ³ny

ochrana druhov